![auditory ossicles function auditory ossicles function](https://image1.slideserve.com/2242895/the-internal-cochlea-n.jpg)
Hair cells normally have a small influx of K + at rest, so there is some baseline activity in the afferent neurons. Press the "play" button to see the mechanical-to-electrical transduction. This in turn causes neurotransmitter release at the basal end of the hair cell, eliciting an action potential in the dendrites of the VIIIth cranial nerve. An inward K + current depolarizes the cell, and opens voltage-dependent calcium channels. This mechanism transduces mechanical energy into neural impulses. Opening these channels allows an influx of potassium, which in turns opens calcium channels that initiates the receptor potential. When the cilia are bent toward the tallest one, the channels are opened, much like a trap door. The tip links function like a string connected to a hinged hatch.
![auditory ossicles function auditory ossicles function](https://www.osha.gov/SLTC/images/middle_ear.gif)
There are tiny thread-like connections from the tip of each cilium to a non-specific cation channel on the side of the taller neighboring cilium. These cilia increase in length along a consistent axis. Cilia emerge from the apical surface of hair cells. Tight junctions between hair cells and the nearby supporting cells form a barrier between endolymph and perilymph that maintains the ionic imbalance.įigure 12.1 illustrates the process of mechanical transduction at the tips of the hair cell cilia. This actively maintained ionic imbalance provides an energy store, which is used to trigger neural action potentials when the hair cells are moved. The fluid, termed endolymph, which surrounds the hair cells is rich in potassium. (See the chapter on Vestibular System: Structure and Function). Hair cells in the maculae of the saccule and the utricle respond to linear acceleration (gravity). Hair cells in the cristae ampullares in the semicircular ducts respond to angular acceleration (rotation of the head). Hair cells in the Organ of Corti in the cochlea of the ear respond to sound. Several specializations make human hair cells responsive to various forms of mechanical stimulation. In higher vertebrates the internal fluid of the inner ear (not external fluid as in fish) bathes the hair cells, but these cells still sense movements in the surrounding fluid. The hair cell first appeared in fish as part of a long, thin array along the side of the body, sensing movements in the water. HFS clients enjoy state-of-the-art warehousing, real-time access to critical business data, accounts receivable management and collection, and unparalleled customer service.The key structure in the vertebrate auditory and vestibular systems is the hair cell. HFS provides print and digital distribution for a distinguished list of university presses and nonprofit institutions. MUSE delivers outstanding results to the scholarly community by maximizing revenues for publishers, providing value to libraries, and enabling access for scholars worldwide. Project MUSE is a leading provider of digital humanities and social sciences content, providing access to journal and book content from nearly 300 publishers. With warehouses on three continents, worldwide sales representation, and a robust digital publishing program, the Books Division connects Hopkins authors to scholars, experts, and educational and research institutions around the world. With critically acclaimed titles in history, science, higher education, consumer health, humanities, classics, and public health, the Books Division publishes 150 new books each year and maintains a backlist in excess of 3,000 titles.
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